Efficacy of sulfamethoxypyridazine in a murine model of Pneumocystis carinii pneumonia.

نویسندگان

  • M S Bartlett
  • M M Shaw
  • J W Smith
  • S R Meshnick
چکیده

Sulfamethoxazole is the component of co-trimoxazole responsible for its efficacy against Pneumocystis carinii pneumonia, but this drug is associated with frequent adverse effects. Sulfamethoxypyridazine is significantly more effective than sulfamethoxazole against a murine model of P. carinii and might be a candidate for testing in infected patients.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 42 4  شماره 

صفحات  -

تاریخ انتشار 1998